Wilson was particularly interested in exploring the juxtaposition between Ivy's noble goal to save the Earth and the 'questionable-to-evil' lengths she will go to achieve it. Poison Ivy's villainy is often motivated by a desire to protect the natural environment from man-made destruction, and the climate change crisis is at the forefront of the story. Before she dies, she sets out to complete one final mission to save the Earth by spreading deadly fungal spores that will end humanity once and for all. Poison Ivy finds herself severely depowered and dying.

The miniseries takes place after the events of the DC Comics ' Fear State' crossover storyline. The first issue was published by DC Comics on June 7, 2022, with subsequent issues published monthly. In February 2023, DC Comics announced that the miniseries would be further expanded into an ongoing series. In August 2022, DC Comics announced that the miniseries would be extended by an additional six issues, with Atagun Ilhan joining Takara in illustrating the second arc. Willow Wilson with art by Marcio Takara, coloring by Arif Prianto, and lettering by Hassan Otsmane-Elhaou. Poison Ivy was originally intended to be a six-issue miniseries written by G. A miniseries starring Poison Ivy was announced by DC Comics in March 2022 as part of the publisher's ' Pride Month' initiative. Beginning in the 1990s, a significant aspect of the character has been her relationship with Harley Quinn.

Poison Ivy is a DC Comics character who was first introduced as a plant-themed Batman villain in 1966. Originally intended as a miniseries, Poison Ivy was later expanded into an ongoing series by DC Comics. Before she dies, Ivy sets out to complete one final mission to save the Earth by destroying the human race.

The series centers on the DC Comics villain Poison Ivy who, following the events of the ' Fear State' crossover, finds herself depowered and dying. Willow Wilson, with art primarily by Marcio Takara. Poison Ivy is an ongoing American comic book written by G. Cover to Poison Ivy #1, art by Jessica Fong

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